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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
23.03
Human Site:
T164
Identified Species:
38.97
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
T164
G
R
T
E
Y
T
I
T
M
Y
D
T
K
T
R
Chimpanzee
Pan troglodytes
XP_511585
968
108684
S161
P
K
E
T
E
A
K
S
K
L
T
P
T
L
Y
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
T257
G
R
T
E
Y
T
I
T
M
Y
D
T
K
T
R
Dog
Lupus familis
XP_853409
975
109686
T164
G
R
T
E
Y
T
I
T
M
Y
D
T
K
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
T166
G
R
T
E
Y
T
I
T
M
Y
D
T
K
T
R
Rat
Rattus norvegicus
XP_573211
965
109012
R164
D
T
K
T
R
E
L
R
W
N
A
T
Y
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
K162
P
E
E
N
V
E
Y
K
M
S
H
F
V
S
N
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
T169
G
R
T
Q
Y
M
I
T
M
Y
D
T
K
S
R
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
D162
E
Y
M
I
T
M
Y
D
T
K
T
Q
E
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
G163
G
R
R
E
K
V
M
G
F
G
D
A
T
V
D
Honey Bee
Apis mellifera
XP_392044
968
110555
Q162
P
R
T
G
Q
R
E
Q
L
L
G
F
D
K
V
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
S176
G
R
T
E
Y
R
V
S
M
F
D
E
K
N
R
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
T186
F
L
G
R
T
E
F
T
V
T
M
F
D
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
E164
I
Q
E
P
S
R
L
E
T
Y
E
T
L
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
6.6
N.A.
80
6.6
N.A.
26.6
13.3
60
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
13.3
N.A.
93.3
13.3
N.A.
33.3
20
80
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
0
50
0
15
0
15
% D
% Glu:
8
8
22
43
8
22
8
8
0
0
8
8
8
0
0
% E
% Phe:
8
0
0
0
0
0
8
0
8
8
0
22
0
8
0
% F
% Gly:
50
0
8
8
0
0
0
8
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
36
0
0
0
0
0
0
8
8
% I
% Lys:
0
8
8
0
8
0
8
8
8
8
0
0
43
8
0
% K
% Leu:
0
8
0
0
0
0
15
0
8
15
0
0
8
15
0
% L
% Met:
0
0
8
0
0
15
8
0
50
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
8
% N
% Pro:
22
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
8
8
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
0
58
8
8
8
22
0
8
0
0
0
0
0
0
50
% R
% Ser:
0
0
0
0
8
0
0
15
0
8
0
0
0
22
0
% S
% Thr:
0
8
50
15
15
29
0
43
15
8
15
50
15
29
8
% T
% Val:
0
0
0
0
8
8
8
0
8
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
43
0
15
0
0
43
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _